Pamela is introduced to everyone as the adoptive daughter of Jesse and Becky. She is named after Pam Tanner.
While Becky is away Jesse is looking after Pamela solo but she won't sleep. Jesse give Pamela her binky (dummy/pacifier), her bibby (blanket) and her woobie (doll) but she still won't go to sleep. Jesse tries to put her and Tommy in the same bed, now neither of them will go to sleep. After Jesse ties her and Tommy to the kitchen bar stool and gives them paper and pens to draw with, they draw all over the kitchen counter and themselves.
Jesse, D.J. and Stephanie sing her to sleep.
Becky arrives with Pamela to spend the day with Stephanie. Pamela and Tommy play in the backyard on the slide and in a pool of balls together.
Danny, Jesse, Joey, Becky and Pamela arrive for the 30th Anniversary of when Joey and Jesse first moved in, which they call the 30th Dad-iversary. While Danny, Jesse, Joey, D.J., Stephanie along with Kimmy all get in Danny's rent-a-car for a drive Becky stays with the kids.
When Stephanie sees Jesse having a weird dance party in the backyard with Pamela, Tommy and Fernando, she believes the first part of her dream has come true. Later Tommy and Pamela put chewing gum in each others hair.
Becky chases Tommy and Pamela around outside after they take her shoes.
Pamela attends the 80s-themed costumed 30th Dad-iversary party at the Smash Club along with Danny, Jesse, Joey, D.J., Stephanie, Becky, Kimmy, Fernando, Jackson, Ramona, Max, Tommy, Steve, Jimmy, Cosmo, Rose, Rocki, Vicki and the Rippers.
Jesse leads the sing-along with 'Itsy-Bitsy Spider' at 'Mommy and Me'. He has sang all over the world but nothing compares to singing to his little girl. When Jesse tells Becky he didn't let any of the mothers touch his hair, Pamela let's the truth out.
Stephanie looks after Pamela while Becky and Jesse have a date night.
Jesse tries to get Tommy and Pamela to sleep after giving them each a glass of warm milk containing Benadryl. But when D.J., Jackson, Ramona and Max arrive home cheering, Tommy and Pamela refuse. Jesse has to get to the Smash Club so he leaves Pamela with D.J. while Becky's out of time. D.J. offers to look after Pamela again the next day but Becky has set Jesse and Pamela up with a 'Daddy and Me' class.
Jesse meets another dad, Ben who assumes Jesse is Pamela's grandfather so Jesse sets him straight. At game time while the other children play with tech, Jesse goes 'old school' by giving Pamela a ball. Pamela kicks the ball and chases after it.
D.J., Stephanie, Kimmy, Jackson, Ramona, Max, Tommy, Fernando, Steve, Jimmy, Pamela and Cosmo are in attendance at the gender reveal party when Jesse arrives with Ben.
Jackson, Ramona, Max, and Tommy eat breakfast when Jesse arrives with Pamela who was bitten at school the day before. When her teacher won't tell Jesse who bit Pamela, he decides to find out himself. Pamela shows Ramona her Band-Aid. Ramona takes Pamela to get some candy from her secret stash.
Jesse gathers Jackson, Ramona, and Max because he is having an after-school playdate/sting operation to find out who bit Pamela. He needs them to do recon - pass out a cookie to a potential perpetrator. That way Jesse can match the bite mark to the bite mark on Pamela's arm. The doorbell rings and parents enter with their children.
Jesse offers Finn a slice of sweet apple. After Finn takes a bite Jesse takes the slice off him and finds Pamela in the kitchen watching Stephanie make dinner for Jimmy. Jesse believes the bite marks are a perfect match. Jesse accuses Finn of biting Pamela at school the previous day. Ben blurts out that Finn wasn't at school because they went to Disneyland. Jesse catches Pamela biting her own arm. Pamela likes Band-Aids so much she bites herself. Jesse explains all Pamela needs to do is ask and he'll give her all the Band-Aids she wants.
Everyone stands as the wedding ceremony begins. Jackson, Ramona, Max, and Tommy wait along side Fernando, Steve, and Jimmy for the brides-to-be. First Joey walks Kimmy, then Jesse walks Stephanie, and last Danny walks D.J. down the aisle. Danny kisses his daughters before sitting with Joey Jesse, and Pamela. Jesse asks Danny for his name to go on his gift. Danny's gift was paying for the wedding. Joey inquires as to if Danny found a minister. Girls are thrilled to discover Joey McIntyre will be officiating their wedding. Joey McIntyre announces he is there to marry three New Kids superfans to their grooms. The couples wrote their own vows. Kimmy and Fernando go first, followed by Stephanie and Jimmy, and last D.J. and Steve. Joey McIntyre cries over the vows, he thought Please Don't Go Girl was romantic. D.J. Stephanie, and Kimmy say "I do" as they place rings on their respective grooms fingers. Fernando, Steve, and Jimmy say "I do" as they place rings on their respective brides fingers. Joey McIntyre pronounces the couples "husbands and wives". All guests stand up, clap, and cheer the newlyweds. Lisa Loeb plays guitar and sings First Day of my Life. The newlyweds share the first dance together as guests watch. Joey gives the first toast. Jesse gives the next toast. D.J. Stephanie, and Kimmy throw their bouquets. Ramona, Lola, and CJ catch them. Danny gives his toast.
- She is adopted